Posted 18.07.2012 12:16:33 UTC
Updated 18.07.2012 12:16:33 UTC
The genetic mutation is proved to have blocked a protein residue in brain which causes Alzheimer’s.
Alzheimer’s is a kind of dementia which impairs mental abilities leading the loss of memory and speaking as well as change in behavior for worse.
Icelandic scientists made the latest contribution into the treatment of the disease that has become one of the most important health problems.
Scanning the genetic map of 1.800 people, the researchers have identified a genetic mutation which lacks in people without Alzerheimer’s.
“We realized that in conditions which BACE enzymes were absent, no Alzerheimer’s had been developed. That enzyme affects the brain causing plaque which turns into Alzheimer’s.”
Icelandic researchers conducted the study on the biological data of people over 85 and showing no signs of Alzerhimer’s.
The residue of a protein called amyloyd beta, which causes a kind of plaque in the brain, was seen around 40% less in people without Alzheimer’s.
Besides, the lucky group was also observed less prone to develop age-related cognitive malfunctioning.
First trials for a drug targeting this protein residue in brain have been tested positive.
Such developments in the treatment for Alzheimer’s and discoveries on the origins of the disease give hope in the battle against the illness.
The disease is the most common form of dementia, affecting over 24 million people globally.
There are no licensed drugs that can slow the progression of Alzheimer's, and currently approved medications only treat symptoms.